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院長・スタッフ紹介

　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　

院長紹介

大西勝也

資格・認定医・専門医

  • 医学博士
  • 日本内科学会認定　内科専門医
  • 日本循環器病学会認定　循環器専門医
  • 日本医師会認定　産業医
  • アメリカ心臓病学会正規会員：
  • Fellowship of American College of Cardiology(FACC)
  • ヨーロッパ心臓病学会正規会員：
  • Fellowship of European Society of Cardiology(FESC)
  • 三重大学大学院循環器科内科　客員教授
  • 大阪大学大学院医学系研究科　循環器内科学　招聘教員
　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　

主な勤務先

  • 三重大学附属病院（内科、循環器腎臓内科）
  • 済生会松阪総合病院
  • 松阪中央総合病院
  • 津地方家庭裁判所
  • 茅ヶ崎徳洲会病院（神奈川県）
  • Wake Forest大学（米国）

スタッフの紹介

院長　　大西　勝也
（日本内科学会認定 内科認定医／日本医師会認定 産業医）
理事長　大西　正文
（日本内科学会認定 内科認定医／日本医師会認定 産業医）
内視鏡専門医
（三重大学附属病院消化器内科：毎週金曜日）
乳腺外科医
（三重大学附属病院乳腺外科：隔週木曜日）
看護師
三重大学附属病院、循環器内科病棟・胸部外科病棟勤務歴のある看護師達や、
介護資格のある看護師など５名
事務員
医療事務の資格を有する事務員３名

院長の主な医師向け著作物のご紹介

著書（2014－2016）

【単著】
  • 「高血圧治療に何か抜けていませんか？」（先端医学社、2016）
  • 「「息切れ」を極める! : Dr.大西が教える心不全とCOPDの治療の法則」（メディカ出版、2014）
  • 「カテーテル時代に知っておきたい 新しい心血行動態入門：いちから学びたい人にDr.大西から80のクエスチョン」（メディカ出版、2014）
【編集】
  • 「真っ向勝負の大動脈狭窄症・閉鎖不全症　6人のエースがすべてを語りつくす」（メディカ出版、2016）
  • 「いま、なぜ心不全ですか？: U40心不全ネットワークにDr.大西が聞いてみた」（メディカ出版2015）
【共著】
  • 実臨床で役立つ血圧測定の工夫と実践　血圧手帳の活用
    （『最新知見をアップデート　血圧変動エビデンス＆プラクティス』編集:楽木宏美、先端医療社、2016）
  • 胸水・腹水は右心不全のサインか？
    （『右心不全を識り評価して治療に活かす』編集: 中村一文、監修: 松﨑益德、責任編集: 伊藤浩・筒井裕之、文光堂、2016）
  • 急性心不全の疫学・病態　病態　肺うっ血を来す血行動態異常
    （『ここが知りたい 急性心不全の救急・集中治療管理』編集: 佐藤幸人、中外医学社、2016）
  • 心不全の集中治療に必要な検査　胸部X線写真
    （『ここが知りたい　急性心不全の救急・集中治療管理』編集: 佐藤幸人、中外医学社、2016）
  • どのような病態に強心薬が必要か？－血行動態の観点から
    （『ここが知りたい 強心薬のさじ加減』編集: 北風政史、中外医学社、2016）
  • チーム医療に必要な検査：X線
    （『最強！心不全チーム医療 スペシャリスト集団になる』編集: 佐藤幸人、メディカ出版、2014）
  • ここだけ押さえよう 心血行動態
    （『臨床心不全のいちばん大事なところ60』編集: 佐藤幸人、メディカ出版、2014）

総説（2014-2016）

  • 病態生理からみたHFpEFとHFrEFの違い（Heart View 20: 2016）
  • HFpEF(左室駆出率の保たれた心不全)には、治療法がないのか？（救急・集中治療 28: 2016）
  • 座談会 心不全のチーム医療－病院から、地域から－（Cardiac Practice 27: 2016）
  • interview診療室の窓辺から（血圧 22: 2015）
  • 心不全の検査（HEART nursing 27: 2015）
  • "循環器専門のプライマリケア医が診るCOPD"はどこが違う!?（明日の臨床 27: 2015）
  • 左心不全の危険因子としてのCOPD（呼吸と循環 63: 2015
  • TACOの危険因子 左室駆出率が保たれている心不全(拡張性心不全)（医学のあゆみ 253: 2015）
  • 慢性心不全の病態と診断 慢性心不全の血行動態（カレントテラピー 33: 2015）
  • 全身疾患COPDの治療と対策 COPD患者の循環器疾患・CKDの治療（内科 113: 2014）
  • 胸部X線検査で何を見る?（jmed mood 30: 2014）
  • 心不全の検査（HEART nursing 27: 2014）
  • COPD患者の循環器疾患・CKDの治療（内科 113: 2014）

英語論文(Publications in Peer-Reviewed Journals)

  • The relationship between the COPD Assessment Test score and airflow limitation in Japan in patients aged over 40 years with a smoking history.
    Yoshimoto D, Nakano Y, Onishi K, Hagan G, Jones P.
    Int J Chron Obstruct Pulmon Dis. 2014 Dec 9;9:1357-63. doi: 10.2147/COPD.S61265.
  • Prognostic value of serum parathyroid hormone level in acute decompensated heart failure.
    Sugimoto T, Dohi K, Onishi K, Yamada T, Horiguchi M, Takamura T, Kawamura A, Seko T, Nakamura M, Kasai A, Ito M.
    Circ J. 2014;78(11):2704-10.
  • Prevalence of airflow limitation in outpatients with cardiovascular diseases in Japan.
    Onishi K, Yoshimoto D, Hagan GW, Jones PW.
    Int J Chron Obstruct Pulmon Dis. 2014 May 29;9:563-8. doi: 10.2147/COPD.S59962.
  • Detection of coronary artery disease using coronary flow velocity reserve by transthoracic Doppler echocardiography versus multidetector computed tomography coronary angiography: influence of calcium score.
    Kakuta K, Dohi K, Yamada T, Yamanaka T, Kawamura M, Nakamori S, Nakajima H, Tanigawa T, Onishi K, Yamada N, Nakamura M, Ito M.
    J Am Soc Echocardiogr. 2014 Jul;27(7):775-85. doi: 10.1016/j.echo.2014.02.012.
  • Relation of risk factors with response to carvedilol in heart failure with preserved ejection fraction - a report from the Japanese Diastolic Heart Failure Study (J-DHF).
    Yamamoto K, Origasa H, Suzuki Y, Takahashi T, Shinozaki T, Watanabe T, Sakata Y, Izumi C, Taira K, Hori M; J-DHF Investigators..
    J Cardiol. 2014 Jun;63(6):424-31. doi: 10.1016/j.jjcc.2013.10.014.
  • Changes in plasma levels of B-type natriuretic peptide with acute exacerbations of chronic obstructive pulmonary disease.
    Nishimura K, Nishimura T, Onishi K, Oga T, Hasegawa Y, Jones PW.
    Int J Chron Obstruct Pulmon Dis. 2014;9:155-62
  • Myocardial perfusion reserve is impaired in patients with chronic obstructive pulmonary disease: a comparison to current smokers.
    Nakamori S, Onishi K, Ishida M, Nakajima H, Yamada T, Nagata M, Kitagawa K, Dohi K, Nakamura M, Sakuma H,?Ito M.
    Eur Heart J Cardiovasc Imaging. 2014;15:180-8
  • Hemodynamic and pathophysiological characteristics of intradialytic blood pressure elevation in patients with end-stage renal disease.
    Oosugi K, Fujimoto N, Dohi K, Machida H,?Onishi K, Takeuchi M, Nomura S, Takeuchi H, Nobori T,?Ito M. Hypertens Res. 2014 Feb;37(2):158-65.
  • An anomalous presentation of tetralogy of Fallot with pulmonary atresia surviving to the age of 62 years.
    Nakamori S, Dohi K, Tanigawa T,?Onishi K,?Ito M.
    Eur Heart J Cardiovasc Imaging. 2013 Nov;14(11):1119.?
  • Quantifying longitudinal right ventricular dysfunction in patients with old myocardial infarction by using speckle-tracking strain echocardiography.
    Konishi K, Dohi K, Tanimura M, Sato Y, Watanabe K, Sugiura E, Kumagai N, Nakamori S, Nakajima H, Yamada T,?Onishi K, Nakamura M, Nobori T,?Ito M.
    Cardiovasc Ultrasound. 2013 Jun 27;11:23. doi: 10.1186/1476-7120-11-23
  • Echocardiographic estimation of pulmonary capillary wedge pressure using the combination of diastolic annular and mitral inflow velocities. Sugimoto T, Dohi K, Tanabe M, Watanabe K, Sugiura E, Nakamori S, Yamada T, Onishi K, Nakamura M, Nobori T,Ito M.
    J Echocardiogr. 2013 Mar;11(1):1-8.
  • Ventricular function and dyssynchrony quantified by speckle-tracking echocardiography in patients with acute and chronic right ventricular pressure overload. Ichikawa K, Dohi K, Sugiura E, Sugimoto T, Takamura T, Ogihara Y, Nakajima H, Onishi K, Yamada N, Nakamura M, Nobori T,Ito M.
    J Am Soc Echocardiogr. 2013 May;26(5):483-92.?
  • Interrelationship between haemodynamic state and serum intact parathyroid hormone levels in patients with chronic heart failure.
    Sugimoto T, Dohi K,?Onishi K, Watanabe K, Sato Y, Sugiura E, Nakamori S, Nakajima H, Nakamura M,?Ito M.
    Heart. 2013 Jan;99(2):111-5.
  • Improving Drug Adherence Using Fixed Combinations Caused Beneficial Treatment Outcomes and Decreased Health-Care Costs in Patients with Hypertension.
    Kumagai N,?Onishi K, Hoshino K, Nakamori S, Kitai T, Yazu T, Oota M, Ueda Y, Hiraoka N, Okamoto S, Yamada T, Dohi K, Nakamura M,?Ito M.
    Clin Exp Hypertens. 2013;35(5):355-60
  • Short-term effects of low-dose tolvaptan on hemodynamic parameters in patients with chronic heart failure.
    Watanabe K, Dohi K, Sugimoto T, Yamada T, Sato Y, Ichikawa K, Sugiura E, Kumagai N, Nakamori S, Nakajima H, Hoshino K, Machida H, Okamoto S,?Onishi K, Nakamura M, Nobori T,?Ito M.
    J Cardiol. 2012 Dec;60(6):462-9. doi: 10.1016/j.jjcc.2012.09.002. Epub 2012 Oct 12.
  • Impaired myocardial perfusion reserve in patients with fatty liver disease assessed by quantitative myocardial perfusion magnetic resonance imaging.
    Nakamori S,?Onishi K, Nakajima H, Yoon YE, Nagata M, Kurita T, Yamada T, Kitagawa K, Dohi K, Nakamura M, Sakuma H,?Ito M.
    Circ J. 2012;76(9):2234-40. Epub 2012 Jun 2.
  • Silent inflammation of an abdominal aortic aneurysm.
    Nakamori S, Nakamura M,?Onishi K,?Ito M.
    Intern Med. 2012;51(8):995-6. Epub 2012 Apr 15. No abstract available.
  • Comparison of coronary flow velocity reserve measurement by transthoracic Doppler echocardiography with 320-row multidetector computed tomographic coronary angiography in the detection of in-stent restenosis in the three major coronary arteries.
    Kakuta K, Dohi K, Yamada T, Yamanaka T, Kawamura M, Nakamori S, Nakajima H, Tanigawa T, Onishi K Yamada N, Nakamura M, Nobori T,?Ito M.
    Am J Cardiol. 2012 Jul 1;110(1):13-20. doi: 10.1016/j.amjcard.2012.02.041. Epub 2012 Mar 28.
  • Prevalence and signal characteristics of late gadolinium enhancement on contrast-enhanced magnetic resonance imaging in patients with takotsubo cardiomyopathy.
    Nakamori S, Matsuoka K,?Onishi K, Kurita T, Ichikawa Y, Nakajima H, Ishida M, Kitagawa K, Tanigawa T, Nakamura T,?Ito M, Sakuma H.
    Circ J. 2012;76(4):914-21. Epub 2012 Jan 27.
  • Impact of chronic kidney disease on the presence and severity of aortic stenosis in patients at high risk for coronary artery disease.
    Masuda C, Dohi K, Sakurai Y, Bessho Y, Fukuda H, Fujii S, Sugimoto T, Tanabe M,?Onishi K, Shiraki K,?Ito M, Nobori T.
    Cardiovasc Ultrasound. 2011 Nov 16;9:31. doi: 10.1186/1476-7120-9-31.
  • Usefulness of tissue characterization by cardiac magnetic resonance imaging as a complementary method for evaluation of cardiac malignant lymphoma.
    Sato K, Kurita T, Nakamori S, Ichikawa Y, Mastuoka K, Tanigawa T,?Onishi K, Sakuma H,?Ito M.
    Int J Cardiol. 2012 Feb 9;154(3):e52-3.
  • Guidelines for the Diagnosis and Treatment of Cardiovascular Diseases
    (2010 Joint Working Groups Report) [Digest Version]Guidelines for Treatment of Acute Heart Failure (JCS 2011) Izumi T, the Japanese Circulation Society Joint Working Groups performed in 2010, Circ J 2011
  • Reversible left ventricular regional non-uniformity quantified by speckle-tracking displacement and strain imaging in patients with acute pulmonary embolism.
    Takamura T, Dohi K,?Onishi K, Sakurai Y, Ichikawa K, Tsuji A, Ota S, Tanabe M, Yamada N, Nakamura M, Nobori T,?Ito M.
    J Am Soc Echocardiogr. 2011 Jul;24(7):792-802. doi: 10.1016/j.echo.2011.03.004. Epub 2011 Apr 9.
  • Role of haemodialytic therapy on left ventricular mechanical dyssynchrony in patients with end-stage renal disease quantified by speckle-tracking strain imaging.
    Murata T, Dohi K,?Onishi K, Sugiura E, Fujimoto N, Ichikawa K, Ishikawa E, Nakamura M, Nomura S, Takeuchi H, Nobori T,?Ito M.
    Nephrol Dial Transplant. 2011 May;26(5):1655-61. doi: 10.1093/ndt/gfq590. Epub 2010 Sep 23.
  • Hypertension impairs myocardial blood perfusion reserve in subjects without regional myocardial ischemia.
    Nakajima H,?Onishi K, Kurita T, Ishida M, Nagata M, Kitagawa K, Dohi K, Nakamura M, Sakuma H,?Ito M.
    Hypertens Res. 2010 Nov;33(11):1144-9. doi: 10.1038/hr.2010.140. Epub 2010 Aug 5.
  • Left ventricular contraction-relaxation coupling in normal, hypertrophic, and failing myocardium quantified by speckle-tracking global strain and strain rate imaging.
    Takamura T, Dohi K,?Onishi K, Tanabe M, Sugiura E, Nakajima H, Ichikawa K, Nakamura M, Nobori T,?Ito M.
    J Am Soc Echocardiogr. 2010 Jul;23(7):747-54. doi: 10.1016/j.echo.2010.04.005.
  • Vegetation with ventricular septal defect detected by cardiac magnetic resonance imaging.
    Kurita T, Tanabe M, Kitagawa K, Onishi K, Shimpo H, Sakuma H,?Ito M.
    Circ J. 2010 Mar;74(3):592-3. Epub 2010 Jan 14. No abstract available.
  • Unique myocardial fibrosis pattern by late gadolinium enhanced magnetic resonance imaging in a patient with isolated noncompaction of the ventricular myocardium.
    Kurita T, Matsuoka K, Hoshida K, Nakamori S, Ichikawa Y, Tanigawa T,?Onishi K, Nakamura T, Sakuma H,?Ito M.
    Circ J. 2010 Feb;74(2):381-2. Epub 2009 Dec 22. No abstract available.
  • Overexpression of myosin phosphatase reduces Ca(2+) sensitivity of contraction and impairs cardiac function.
    Mizutani H, Okamoto R, Moriki N, Konishi K, Taniguchi M, Fujita S, Dohi K,?Onishi K, Suzuki N, Satoh S, Makino N, Itoh T, Hartshorne DJ,?Ito M.
    Circ J. 2010 Jan;74(1):120-8. Epub 2009 Dec 7.
  • Incremental prognostic values of serum tenascin-C levels with blood B-type natriuretic peptide testing at discharge in patients with dilated cardiomyopathy and decompensated heart failure.
    Fujimoto N,?Onishi K, Sato A, Terasaki F, Tsukada B, Nozato T, Yamada T, Imanaka-Yoshida K, Yoshida T,?Ito M, Hiroe M.
    J Card Fail. 2009 Dec;15(10):898-905. doi: 10.1016/j.cardfail.2009.06.443. Epub 2009 Aug 26.
  • Reversible right ventricular regional non-uniformity quantified by speckle-tracking strain imaging in patients with acute pulmonary thromboembolism.
    Sugiura E, Dohi K,?Onishi K, Takamura T, Tsuji A, Ota S, Yamada N, Nakamura M, Nobori T,?Ito M.
    J Am Soc Echocardiogr. 2009 Dec;22(12):1353-9. doi: 10.1016/j.echo.2009.09.005.
  • Regional myocardial perfusion reserve determined using myocardial perfusion magnetic resonance imaging showed a direct correlation with coronary flow velocity reserve by Doppler flow wire.
    Kurita T, Sakuma H,?Onishi K, Ishida M, Kitagawa K, Yamanaka T, Tanigawa T, Kitamura T, Takeda K,?Ito M.
    Eur Heart J. 2009 Feb;30(4):444-52. doi: 10.1093/eurheartj/ehn521. Epub 2008 Dec 19.
  • Conventional therapy with an ACE inhibitor diminishes left ventricular dyssynchrony during the progression of heart failure.
    Kurita T,?Onishi K, Dohi K, Takamura T, Fujimoto N, Tanigawa T, Imanaka-Yoshida K, Wada H, Nobori T,?Ito M.
    Int J Cardiol. 2010 Apr 1;140(1):48-54. doi: 10.1016/j.ijcard.2008.10.047. Epub 2008 Dec 7.
  • Serum intact parathyroid hormone levels predict hospitalisation for heart failure.
    Sugimoto T, Tanigawa T,?Onishi K, Fujimoto N, Matsuda A, Nakamori S, Matsuoka K, Nakamura T, Koji T,?Ito M.
    Heart. 2009 Mar;95(5):395-8. doi: 10.1136/hrt.2008.147652. Epub 2008 Nov 10.
  • Hemodynamic characteristics of patients with diastolic heart failure and hypertension.
    Fujimoto N,?Onishi K, Dohi K, Tanabe M, Kurita T, Takamura T, Yamada N, Nobori T,?Ito M.
    Hypertens Res. 2008 Sep;31(9):1727-35. doi: 10.1291/hypres.31.1727.
  • Response to: Study of Left Ventricular Long Axis Function in Patients with Hypertensive Response to Exercise.
    Takamura T,?Onishi K, Sugimoto T, Kurita T, Fujimoto N, Dohi K, Tanigawa T, Isaka N, Nobori T,?Ito M.
    Hypertens Res. 2008;31(7):1486. No abstract available.
  • Elevated levels of soluble fibrin in patients with venous thromboembolism.
    Tsuji A, Wada H, Matsumoto T, Abe Y, Ota S, Yamada N, Sugiyama T, Sudo A,?Onishi K, Nakatani K, Uchida A,?Ito M, Suzuki K, Nobori T.
    Int J Hematol. 2008 Nov;88(4):448-53. doi: 10.1007/s12185-008-0173-5. Epub 2008 Oct 4.
  • Biventricular pacing worsened dyssynchrony in heart failure patient with right-bundle branch block.
    Tanabe M, Dohi K,?Onishi K, Nakata T, Sato Y, Nakajima H, Takamura T, Miyahara M, Nakamura M, Takeda K,?Ito M.
    Int J Cardiol. 2010 Feb 4;138(3):e47-50. doi: 10.1016/j.ijcard.2008.06.063. Epub 2008 Aug 15.
  • Exaggerated hypertensive response to exercise in patients with diastolic heart failure.
    Kato S,?Onishi K, Yamanaka T, Takamura T, Dohi K, Yamada N, Wada H, Nobori T,?Ito M.
    Hypertens Res. 2008 Apr;31(4):679-84. doi: 10.1291/hypres.31.679.
  • Molecular diagnosis of prosthetic valve endocarditis with aorto-right atrial fistula.
    Takamura T, Tanabe M,?Onishi K, Yamazato S, Nakamura A, Onoda K, Wada H, Shimpo H, Nobori T,?Ito M.
    Int J Cardiol. 2009 Jun 12;135(1):e13-5. doi: 10.1016/j.ijcard.2008.03.029. Epub 2008 Jun 25.
  • Tenascin-C may aggravate left ventricular remodeling and function after myocardial infarction in mice.
    Nishioka T,?Onishi K Shimojo N, Nagano Y, Matsusaka H, Ikeuchi M, Ide T, Tsutsui H, Hiroe M, Yoshida T,?Imanaka-Yoshida K.
    Am J Physiol Heart Circ Physiol. 2010 Mar;298(3):H1072-8. doi: 10.1152/ajpheart.00255.2009. Epub 2010
  • Incremental prognostic values of serum tenascin-C levels with blood B-type natriuretic peptide testing at discharge in patients with dilated cardiomyopathy and decompensated heart failure.
    Fujimoto N, Onishi K, Sato A, Terasaki F, Tsukada B, Nozato T, Yamada T,?Imanaka-Yoshida K, Yoshida T, Ito M, Hiroe M.
    J Card Fail. 2009 Dec;15(10):898-905. doi: 10.1016/j.cardfail.2009.06.443. Epub 2009 Aug 26.
  • Role of radial strain and displacement imaging to quantify wall motion dyssynchrony in patients with left ventricular mechanical dyssynchrony and chronic right ventricular pressure overload.
    Dohi K,?Onishi K, Gorcsan J 3rd, Lopez-Candales A, Takamura T, Ota S, Yamada N,?Ito M. Am J Cardiol. 2008 Apr 15;101(8):1206-12. doi: 10.1016/j.amjcard.2007.11.077. Epub 2008 Mar 4.
  • Elevated levels of soluble fibrin in patients with venous thromboembolism.
    Tsuji A,?Wada H, Matsumoto T, Abe Y, Ota S, Yamada N, Sugiyama T, Sudo A,?Onishi K, Nakatani K, Uchida A, Ito M, Suzuki K, Nobori T.
    Int J Hematol. 2008 Nov;88(4):448-53. doi: 10.1007/s12185-008-0173-5. Epub 2008 Oct 4.
  • Patients with a hypertensive response to exercise have impaired left ventricular diastolic function.
    Takamura T,?Onishi K, Sugimoto T, Kurita T, Fujimoto N, Dohi K, Tanigawa T, Isaka N, Nobori T,?Ito M.
    Hypertens Res. 2008 Feb;31(2):257-63. doi: 10.1291/hypres.31.257.
  • Correlation between late gadolinium enhancement and diastolic function in hypertrophic cardiomyopathy assessed by magnetic resonance imaging.
    Motoyasu M, Kurita T,?Onishi K, Uemura S, Tanigawa T, Okinaka T, Takeda K, Nakano T,?Ito M, Sakuma H.
    Circ J. 2008 Mar;72(3):378-83.
  • A case of clover-shaped left ventricular non-compaction.
    Kurita T,?Onishi K, Ogawa T, Kasai A, Sakuma H,?Ito M.
    Eur Heart J. 2008 Feb;29(4):569. Epub 2007 Oct 30. No abstract available.
  • Two cases of dilated cardiomyopathy with right ventricular wall degeneration demonstrated by late gadolinium enhanced MRI.
    Kurita T, Onishi K Motoyasu M, Kitamura T, Takamura T, Fujimoto N, Tanabe M, Dohi K, Tanigawa T, Isaka N,?Ito M, Sakuma H.
    Int J Cardiol. 2008 Sep 16;129(1):e21-3. Epub 2007 Aug 8.
  • Eplerenone attenuates myocardial fibrosis in the angiotensin II-induced hypertensive mouse: involvement of tenascin-C induced by aldosterone-mediated inflammation.
    Nishioka T, Suzuki M,?Onishi K, Takakura N, Inada H, Yoshida T, Hiroe M,?Imanaka-Yoshida K.
    J Cardiovasc Pharmacol. 2007 May;49(5):261-8.
  • Higher serum tenascin-C levels reflect the severity of heart failure, left ventricular dysfunction and remodeling in patients with dilated cardiomyopathy.
    Terasaki F, Okamoto H,?Onishi K, Sato A, Shimomura H, Tsukada B,?Imanaka-Yoshida K, Hiroe M, Yoshida T, Kitaura Y, Kitabatake A; Study Group for Intractable Diseases by a Grant from the Ministry of Health, Labor and Welfare of Japan.
    Circ J. 2007 Mar;71(3):327-30.
  • Impact of heart rate on mechanical dyssynchrony and left ventricular contractility in patients with heart failure and normal QRS duration.
    Kurita T,?Onishi K, Dohi K, Tanabe M, Fujimoto N, Tanigawa T, Setsuda M, Isaka N, Nobori T,?Ito M.
    Eur J Heart Fail. 2007 Jun-Jul;9(6-7):637-43. Epub 2007 Apr 27.
  • Improvement of left ventricular mechanical dyssynchrony associated with restoration of left ventricular function in a patient with fulminant myocarditis and complete left bundle branch block.
    Takamura T, Dohi K,?Onishi K, Kurita T, Tanabe M, Tanigawa T, Isaka N,?Ito M.
    Int J Cardiol. 2008 Jun 23;127(1):e8-11. Epub 2007 Apr 12.
  • Single beat determination of regional myocardial strain measurements in patients with atrial fibrillation.
    Yamanaka-Funabiki K,?Onishi K, Tanabe M, Dohi K,?Ito M, Ohte N, Nobori T, Nakano T.
    J Am Soc Echocardiogr. 2006 Nov;19(11):1332-7.
  • Antique SVG with two humps: a case of two giant aneurysms of single saphenous vein bypass graft.
    Kurita T, Kitamura T, Yamanaka T, Tanabe M, Dohi K, Tanigawa T,?Onishi K,?Ito M, Isaka N, Nakano T.
    Int J Cardiol. 2007 Mar 20;116(2):e68-70. Epub 2006 Oct 30.
  • Force- and relaxation-frequency relations in patients with diastolic heart failure.
    Yamanaka T,?Onishi K, Tanabe M, Dohi K, Funabiki-Yamanaka K, Fujimoto N, Kurita T, Tanigawa T, Kitamura T,?Ito M, Nobori T, Nakano T.
    Am Heart J. 2006 Nov;152(5):966.e1-7.
  • Cardiac malignant lymphoma with atrial arrhythmias.
    Hirabayashi T, Tanabe M,?Onishi K, Tanigawa T, Kitamura T, Yamada N,?Ito M, Isaka N, Nakano T.
    Int J Cardiol. 2007 Jan 8;114(2):E42-4. Epub 2006 Oct 20. No abstract available.
  • A simple technique to determine thrombopoiesis level using immature platelet fraction (IPF).
    Abe Y,?Wada H, Tomatsu H, Sakaguchi A, Nishioka J, Yabu Y, Onishi K, Nakatani K, Morishita Y, Oguni S, Nobori T.
    Thromb Res. 2006;118(4):463-9. Epub 2005 Oct 25.
  • Newly diagnosed acute aortic dissection: characteristics, treatment modifications, and outcomes.
    Sato F, Kitamura T, Kongo M, Okinaka T, Onishi K,?Ito M, Isaka N, Nakano T.
    Int Heart J. 2005 Nov;46(6):1083-98.
  • Elevated plasma levels of fibrin degradation products by granulocyte-derived elastase in patients with disseminated intravascular coagulation.
    Matsumoto T,?Wada H, Nobori T, Nakatani K,?Onishi K, Nishikawa M, Shiku H, Kazahaya Y, Sawai T, Koike K, Matsuda M.
    Clin Appl Thromb Hemost. 2005 Oct;11(4):391-400.
  • Thrombomodulin accelerates activated protein C production and inhibits thrombin generation in the plasma of disseminated intravascular coagulation patients.
    Wada H, Sakakura M, Kushiya F, Nisikawa M, Onishi K, Nakatani K, Shiku H, Nobori T.
    Blood Coagul Fibrinolysis. 2005 Jan;16(1):17-24.
  • Effects of human atrial natriuretic peptide on cardiac function and hemodynamics in patients with high plasma BNP levels.
    Nakajima K,?Onishi K, Dohi K, Tanabe M, Kurita T, Yamanaka T,?Ito M, Isaka N, Nobori T, Nakano T.
    Int J Cardiol. 2005 Oct 10;104(3):332-7.
  • Assessment of left ventricular systolic function in patients with chronic atrial fibrillation and dilated cardiomyopathy using the ratio of preceding to prepreceding R-R intervals.
    Tanabe M,?Onishi K, Dohi K, Kitamura T,?Ito M, Nobori T, Nakano T.
    Int J Cardiol. 2006 Apr 4;108(2):197-201. Epub 2005 Jun 2.
  • Nitroglycerin improves left ventricular relaxation by changing systolic loading sequence in patients with excessive arterial load.
    Fujimoto N, Onishi K, Tanabe M, Dohi K, Funabiki K, Kurita T, Yamanaka T, Nakajima K,?Ito M, Nobori T, Nakano T.
    J Cardiovasc Pharmacol. 2005 Mar;45(3):211-6.
  • Electron microscopic findings of cardiomyopathy with limb girdle muscular dystrophy.
    Funabiki K, Onishi K, Tanabe M, Kuru S, Konagaya M, Sato F,?Ito M, Nakano T. Int J Cardiol. 2005 Jan;98(1):161-2.
  • Change in filling pattern with preload reduction reflects left ventricular relaxation.
    Tanabe M, Onishi K, Dohi K, Funabiki K, Koji T, Kitamura T,?Ito M, Nobori T, Nakano T.
    Int J Cardiol. 2005 Jan;98(1):67-72.
  • A case of acute myocardial infarction caused by left main trunk disease with dilated cardiomyopathy.
    Ogawa E, Okinaka T, Motoyasu M, Tanabe M, Iwasaki H, Kitamura T,?Onishi K, Isaka N,?Nakano T.
    Int J Cardiol. 2005 Feb 28;98(3):507-8.
  • Enhanced inhibition of L-type Ca2+ current by beta3-adrenergic stimulation in failing rat heart.
    Zhang ZS, Cheng HJ,?Onishi K Ohte N, Wannenburg T,?Cheng CP.
    J Pharmacol Exp Ther. 2005 Dec;315(3):1203-11. Epub 2005 Aug 31.
  • Intravascular hemolysis in aortic stenosis.
    Tsuji A, Tanabe M, Onishi K, Kitamura T, Okinaka T,?Ito M, Isaka N, Nakano T.
    Intern Med. 2004 Oct;43(10):935-8.
  • Two cases of giant aneurysm in coronary-pulmonary artery fistula associated with atherosclerotic change.
    Fujimoto N,?Onishi K, Tanabe M, Koji T, Omichi C, Kato S, Kawasaki A, Nakano T,?Ito M.
    Int J Cardiol. 2004 Dec;97(3):577-8.
  • Combined angiotensin receptor blocker and ACE inhibitor on myocardial fibrosis and left ventricular stiffness in dogs with heart failure.
    Funabiki K,?Onishi K, Dohi K, Koji T, Imanaka-Yoshida K,?Ito M, Wada H, Isaka N, Nobori T, Nakano T.
    Am J Physiol Heart Circ Physiol. 2004 Dec;287(6):H2487-92.
  • Candesartan prevents myocardial fibrosis during progression of congestive heart failure.
    Onishi K Dohi K, Koji T, Funabiki K, Kitamura T, Imanaka-Yoshida K,?Ito M, Nobori T, Nakano T.
    J Cardiovasc Pharmacol. 2004 Jun;43(6):860-7.
  • Bilateral giant coronary aneurysms diagnosed non-invasively by dynamic magnetic resonance imaging.
    Tanabe M,?Onishi K, Hiraoka N, Kitamura T, Okinaka T,?Ito M, Isaka N, Nakano T.
    Int J Cardiol. 2004 Apr;94(2-3):341-2.
  • Effective cardiac resynchronization after Dor procedure and mitral annuloplasty.
    Tanabe M,?Onishi K, Kitamura T, Okinaka T,?Ito M, Isaka N, Hioki I, Onoda K, Yada I, Nakano T. Can J Cardiol. 2004 Mar 15;20(4):449-51.
  • Alternans decay of postextrasystolic potentiation in human left ventricle.
    Tanabe M,?Onishi K, Dohi K,?Ito M, Nakano T, Suga H.
    Jpn J Physiol. 2004 Feb;54(1):87-91.
  • A case of inverted left atrial appendage mimicking a tumor.
    Motoyasu M, Sakuma H, Iwasaki H,?Onishi K, Okinaka T, Isaka N, Takeda K,?Nakano T.
    J Comput Assist Tomogr. 2003 Jul-Aug;27(4):501-4.
  • Addition of angiotensin II receptor antagonist to an ACE inhibitor in heart failure improves cardiovascular function by a bradykinin-mediated mechanism.
    Koji T,?Onishi K Dohi K, Okamoto R, Tanabe M, Kitamura T,?Ito M, Isaka N, Nobori T, Nakano T.
    J Cardiovasc Pharmacol. 2003 Apr;41(4):632-9.
  • Activation of RhoA and inhibition of myosin phosphatase as important components in hypertension in vascular smooth muscle.
    Seko T,?Ito M, Kureishi Y, Okamoto R, Moriki N,?Onishi K, Isaka N, Hartshorne DJ, Nakano T.
    Circ Res. 2003 Mar 7;92(4):411-8. Epub 2003 Feb 6.
  • Circadian rhythm of blood pressure is transformed from a dipper to a non-dipper pattern in shift workers with hypertension.
    Kitamura T,?Onishi K, Dohi K, Okinaka T,?Ito M, Isaka N, Nakano T.
    J Hum Hypertens. 2002 Mar;16(3):193-7.
  • Plasma levels of heparin cofactor II (HCII) and thrombin-HCII complex in patients with disseminated intravascular coagulation.
    Noda A,?Wada H, Kusiya F, Sakakura M, Onishi K, Nakatani K, Gabazza EC, Asahara N, Tsukada M, Nobori T, Shiku H.
    Clin Appl Thromb Hemost. 2002 Jul;8(3):265-71.
  • Effects of therapeutic doses of human atrial natriuretic peptide on load and myocardial performance in patients with congestive heart failure.
    Mizuno O,?Onishi K, Dohi K, Motoyasu M, Okinaka T,?Ito M, Isaka N, Nakano T.
    Am J Cardiol. 2001 Oct 15;88(8):863-6.
  • Multiple pulmonary emboli with pulmonary hypertension caused by effort thrombosis and effective balloon venoplasty of the subclavian vein.
    Isaka N, Yamada N, Araki S, Onishi K, Motoyasu M, Okinaka T,?Ito M, Nakano T.
    Jpn Circ J. 2001 Oct;65(10):920-2.
  • Functional role of endogenous endothelin-1 in congestive heart failure treated with angiotensin II receptor antagonist.
    Dohi K,?Onishi K Kitamura T, Okinaka T,?Ito M, Isaka N, Nakano T.
    Jpn J Physiol. 2001 Aug;51(4):445-53.
  • Upregulation of functional beta(3)-adrenergic receptor in the failing canine myocardium.
    Cheng HJ, Zhang ZS,?Onishi K, Ukai T, Sane DC,?Cheng CP.
    Circ Res. 2001 Sep 28;89(7):599-606.
  • The role of ANG II and endothelin-1 in exercise-induced diastolic dysfunction in heart failure.
    Cheng CP, Ukai T,?Onishi K, Ohte N, Suzuki M, Zhang ZS, Cheng HJ, Tachibana H, Igawa A, Little WC.
    Am J Physiol Heart Circ Physiol. 2001 Apr;280(4):H1853-60.
  • The negative inotropic effect of beta3-adrenoceptor stimulation in the beating guinea pig heart.
    Kitamura T,?Onishi K Dohi K, Okinaka T, Isaka N,?Nakano T.
    J Cardiovasc Pharmacol. 2000 May;35(5):786-90.
  • Endogenous endothelin-1 depresses left ventricular systolic and diastolic performance in congestive heart failure.
    Onishi K, Ohno M, Little WC,?Cheng CP.
    J Pharmacol Exp Ther. 1999 Mar;288(3):1214-22.
  • Functional effects of endogenous bradykinin in congestive heart failure.
    Cheng CP,?Onishi K, Ohte N, Suzuki M, Little WC.
    J Am Coll Cardiol. 1998 Jun;31(7):1679-86.
  • MCI-154, a Ca2+ sensitizer, decreases the oxygen cost of contractility in isolated canine hearts.
    Onishi K, Sekioka K, Ishisu R, Abe Y, Tanaka H, Nakamura M, Ueda Y,?Nakano T.
    Am J Physiol. 1997 Oct;273(4 Pt 2):H1688-95.
  • Restoration of ischemic contractile failure of indo-1-loaded guinea pig heart by a calcium sensitizer, MCI-154.
    Abe Y, Sekioka K, Ishisu R, Onishi K, Ueda Y,?Nakano T.
    J Pharmacol Exp Ther. 1996 Oct;279(1):47-55.
  • Differential effects of EMD-53998 on calcium-pressure relationship in normal and ischemic guinea pig heart.
    Ishisu R, Abe Y,?Onishi K Sekioka K,?Nakano T.
    Am J Physiol. 1996 Jul;271(1 Pt 2):H311-9.
  • Decrease in oxygen cost of contractility during hypocapnic alkalosis in canine hearts.
    Onishi K, Sekioka K, Ishisu R, Tanaka H, Nakamura M, Ueda Y,?Nakano T.
    Am J Physiol. 1996 Jun;270(6 Pt 2):H1905-13.
  • Changes in calcium transient and left ventricular function during positive inotropic stimulation and myocardial ischemia in indo-1-loaded beating guinea pig heart.
    Ishisu R, Abe Y, Onishi K, Ueda Y, Sekioka K,?Nakano T.
    J Pharmacol Toxicol Methods. 1996 Feb;35(1):55-61.
  • Calcium sensitization in perfused beating guinea pig heart by a positive inotropic agent MCI-154.
    Abe Y, Ishisu R,?Onishi K, Sekioka K, Narimatsu A,?Nakano T.
    J Pharmacol Exp Ther. 1996 Feb;276(2):433-9.

国内学会招請講演(2014-2016)

  • 第64回日本心臓病学会学術集会　2016年9月23～25日　東京
    ＜Cardiology Clinic Session＞日本の循環器医療を地域から支える
    • 慢性心不全患者管理のための診診連携における循環器内科クリニックの役割
  • 第39回日本高血圧学会総会　2016年9月30~10月2日　仙台
    ＜ランチョンセミナー＞
    • Hemodynamic Round　－高血圧に伴うHFpEFのアプローチ－
  • 第20回日本心不全学会学術集会　2016年10月7~9日　札幌
    ＜教育講演＞
    • COPDでなぜ左心不全が生じるか？
  • 第65回日本農村医学会学術総会　2016年10月27~28日　志摩
    ＜ランチョンセミナー＞
    • 胸部X線写真で見落とされる高齢者の心不全　－心不全における血圧の意義－
  • 第1回日本心臓リハビリテーション学会近畿地方会　2016年2月27日　京都
    ＜教育講演＞
    • 知っておきたい慢性心不全の運動時の血行動態
  • 第79回日本循環器学会総会・学術集会　2015年4月24~26日　大阪
    ＜Morning Lecture＞
    • How to Improve the Treatment for Chronic Heart Failure in the Clinical Practice
  • 第63回日本心臓病学会学術集会　2015年9月18~20日　横浜
    ＜臨床・実地医家セッションシンポジウム＞
    • ・在宅診療と病診連携を考える：2025年問題に向けて　－実地医家の立場から－
    • ・実地医家が参加するレジストリーから診療の実態を学ぶ　－心房細動の心血行動態－
  • 第19回日本心不全学会学術集会　2015年10月22~24日　大阪
    ＜特別企画U-40合同Case Conference＞
    • 診断は? 手術適応は? 周術期管理はどうする??－Road to Next Generation Heart Team－
    • ミニレクチャー：Constrictive Physiology
    ＜コーヒーブレイクセミナー＞
    • 心血行動態から考える高齢者の高血圧治療
  • 第15回日本NO学会学術集会　2015年6月27日　豊中
    ＜ランチョンセミナー＞
    • 心不全にβ遮断薬を使わない理由
  • 第145回日本循環器学会東海地方会　2015年6月13日　名古屋
    ＜サテライト教育講演＞
    • β遮断薬
  • 第119回日本循環器病学会近畿地方会　2015年6月20日　大阪
    ＜ランチョンセミナー＞
    • 拡張不全は“少しやり過ぎ”くらいがちょうどいい
  • 第120回日本循環器学会近畿地方会　2015年11月28日　大阪
    ＜ランチョンセミナー＞
    • Hemodynamic congestionを意識した心不全管理
  • 第78回日本循環器学会総会・学術集会　2014年3月21-23日　東京
    ＜ファイアダイドセミナー＞β遮断薬療法の6W2Hを、プロフェッショナルが議論する－環境の変化による誤解を懸念して－
    • 特別発言　プライマリ・ケア医の立場から
  • 第20回日本心臓リハビリテーション学会学術集会　2014年7月19-20日　京都
    ＜ランチョンセミナー＞
    • 心不全と呼吸器　－COPD合併患者の治療戦略とは？
  • 第62回日本職業・災害医学会学術大会　2014年11月16日　神戸
    ＜イブニングセミナー＞
    • “呼吸器非専門医が診るCOPD”はどこが違う？

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